Home >> Health >> Pharmacy >> Drugs and Medications >> S >> Selegiline




Selegiline (l-deprenyl, Eldepryl® or even Anipryl® [veterinary]) occurs as drug used for the treatment of early-stage Parkinson's disease and senile dementia. Inside normal clinical drugs these are the selective MAO-B inhibitor, however inside super big drugs (>25mg in a average adult) it loses its specificity & as well inhibits MAO-A. Since these come selective for MAO-B, there is no favorite dietetic restrictions are required when sustaining more MAOI drugs.

Uses
These are occasionally utilized off-label as a nootropic, when well as for its putative life-extending results. These are too reported to positively affect libido, particularly in older males. Selegiline is likewise utilized (at super high dosages relative to man) inside veterinary medicine to treat a consequences of Cushing's disease and so-called "cognitive dysfunction" in dogs.

Mechanism of Action
Selegiline raises dopamine and phenylethylamine levels in the CNS without directly affecting serotonin or norepinephrine. Selegiline could indirectly raise noradrenaline because dopastat may be catabolized within a brain to noradrenaline, although the extent of this is variable. Selegiline metabolizes partially to an inactive stereoisomer of methamphetamine in vivo in levels that, even in case active, come far as well moo to keep around any important outcome. All the same due to this selegiline may are causal agents for false positives for amphetamine/methamphetamine on drug tests.

Legal Issues
Even due to the structural similarity to illegal stimulants, selegiline has been classified as a controlled substance in Japan and thus might simply exist as found by using the prescription or special government license.

Selegine HCl Oral
Patient handout, with links to more technical information on pharmacology, drug interactions, and other topics. [Requires free registration.]

Selegiline [l-deprenyl]
Describes this medication as a mood-brightener.

Eldepryl
Full prescribing information from RxList.






© 2005 GeneralAnswers.org